AccelBio is proud to share the approval of two projects under the FCT Exploratory Projects call: 

  1. Deciphering MicroRNA Mechanisms of Action via High-Dimensional Multiparametric Cell Painting Assay
    A cutting-edge Cell Painting approach to map miRNA mechanisms by matching phenotypic signatures to profiles generated with FDA-approved compounds. 
  1. Exploiting Novel Host-Directed Antimicrobials for Combating Infections by Staphylococcus aureus
    A newly established approach to identify host-directed candidates that may be used alone or in combination with classical antibiotics. 

These projects reinforce our commitment to enabling high-impact translational science and expanding innovative pipelines. 

Under COMPETE P2030, AccelBio has secured approval for Bio-Transfer: Biomedical Knowledge Commercialization Program, a joint initiative led by i3S, AccelBio, and CoLAB Trials. 

Bio-Transfer aims to strengthen biomedical technology transfer and commercialisation through an integrated national framework and five interconnected actions, including: 

The programme will also track the progress of supported startups and consolidate learnings into a community-facing white paper. 

CoLAB AccelBio is pleased to announce that we are officially a partner in BIO-RED, a European Commission-funded consortium. 

Together with a strong network of partners across Europe, BIO-RED will support academic labs and emerging pharma and biotech companies in the development and adoption of green technologies in red biotechnology—accelerating more sustainable innovation across the life sciences value chain. 

If your organisation is developing sustainable biotech solutions, we’d love to connect. 

https://www.linkedin.com/company/bio-red/posts/?feedView=all

CoLAB AccelBio has secured its first European-funded project by joining IMPACT through the Hop-On mechanism. 

IMPACT is an EIC Pathfinder initiative with an ambitious goal: to pave the way for novel therapies for major cardiovascular diseases, by implementing an AI-based integration of clinical and multi-omics data from patients with arrhythmogenic cardiomyopathy (ACM). 

ACM is a genetic condition associated with ventricular arrhythmias and sudden cardiac death, particularly in young people and athletes. As no effective disease-modifying treatments are currently available, IMPACT aims to strengthen the understanding of genotype–phenotype relationships by combining large-scale patient -omics with structural and functional data from in vitro and in vivo models. 

Interested in collaborating on ACM-focused translational research? Get in touch with our team. 

In a groundbreaking project funded by the La Caixa Foundation, AccelBio and Marc Veldhoen’s team, from GiMM, have joined forces to explore a novel strategy for selectively modulating T cell responses. Infectious and inflammatory diseases, whose global prevalence is on the rise, remain among the leading causes of mortality worldwide. Many of these conditions are linked to the activity of T cells, a type of white blood cell critical for coordinating immune responses against pathogens. However, T cells can sometimes become overactive, leading to severe conditions such as fibrosis, chronic obstructive pulmonary disease (COPD), and asthma.

Current treatments often rely on broad-spectrum immunosuppressive drugs, which, while effective, come with significant side effects and an increased risk of infections. This highlights the urgent need for therapies that can selectively inhibit T cell activity without compromising the overall immune response.

Marc Veldhoen’s team has identified a key factor in T cell activation, which the research will investigate as a new therapeutic target. In collaboration with Silvia Almeida and Vânia Cardoso from CoLAB AccelBio, experts in drug discovery, the team will work to identify drug candidates that modulate T cell response while preserving the immune system’s protective functions. This project aims to develop tools to reduce the side effects commonly associated with current treatments for infectious and inflammatory diseases, potentially leading to safer and more effective therapies.

This innovative approach holds promise for advancing targeted therapies that improve patient outcomes in managing complex immune-related conditions.

CoLAB AccelBio is one of the partners in the "Health from Portugal" Mobilizing Agenda, led by Prologica, and approved under the Portuguese Economic Recovery and Resilience Plan (recuperarportugal.gov.pt).

The main aim of the agenda is to position Portugal as a world reference hub in the design, development and production of advanced solutions for the health markets, based on innovation and technology. HfPT will focus on four areas: (i) the development of smart health solutions aimed at the digital medtech segment; (ii) the creation of a national smart health data repository of international reference; (iii) capacity building for the growth and sophistication of the clinical studies segment in the country; and (iv) the creation of solutions that valorise the potential of the ecosystem for collecting and benchmarking clinical data and costs associated with healthcare provision.

Starting date: 01/01/2023
Estimated completion date: 31/12/2025

Eliglible Investment (Agenda): 90,6 million €
Eliglible Investment (AccelBio): 708.779,76 €


O CoLAB AccelBio é um dos parceiros da Agenda Mobilizadora "Health from Portugal", liderada pela Prológica, e aprovada no âmbito do Plano de Recuperação e Resiliência (recuperarportugal.gov.pt).

A agenda HfPT visa posicionar Portugal como um hub de referência mundial na conceção, desenvolvimento e produção de soluções avançadas dirigidas aos mercados da saúde, assentes na inovação e tecnologia. A HfPT incidirá em 4 áreas de aposta: (i) desenvolvimento de soluções smart health dirigidas ao segmento do medtech digital; (ii) criação de um repositório inteligente nacional de dados de saúde de referência internacional; (iii) capacitação para o crescimento e sofisticação do segmento dos estudos clínicos no país; e (iv) criação de soluções que valorizem o potencial do ecossistema de recolha e benchmark de dados clínicos e custos associados à prestação de cuidados de saúde.

Data de inicio: 01/01/2023
Data (prevista) de conclusão: 31/12/2025

Investimento Elegível (Agenda): 90,6 million €
Investimento Elegível (AccelBio): 708.779,76 €

Contact Us

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